Jekyll2026-10-17T00:42:11+08:00https://geneticode.org/feed.xmlGeneticode LabGeneticode Lab develops computational methods that connect genetic sequence to biological function, including protein function annotation and mutation effects.Dong Wangcsdwang@ncepu.edu.cnS2DA-GO published in Frontiers in Genetics2026-07-08T00:00:00+08:002026-07-08T00:00:00+08:00https://geneticode.org/news/s2da-go-publishedS2DA-GO, a sequence-based model for Gene Ontology protein function prediction, is published in Frontiers in Genetics. Dong Wang is a corresponding author.

The method pairs protein language-model embeddings with semantic priors from GO term text, and uses a gradient-decoupled cross-attention branch so sparsely annotated functions interfere less with the shared sequence representation.

Preferred citation, as given in the code repository:

Wang H, Xiang F, Zhang J, Wu T, Wang D, Wang Q, Lu B and Fu F (2026) S2DA-GO: enhancing protein function prediction via gradient-decoupled cross-attention and semantic priors. Front. Genet. 17:1880976. doi: 10.3389/fgene.2026.1880976

]]>Dong Wangcsdwang@ncepu.edu.cn